The way to say the directions in Spanish is the following:

-A la derecha (to the right)
-A la izquierda (to the left)
-Gire a la izquierda/derecha (turn left/right)
-Vaya todo recto (go straight ahead)
-En la proxima esquina (at the next corner)

A some vocabulary that you might want to know:
Norte: North
Sur: South
Este: East
Oeste: West